Regulatory T cell defects in rheumatoid arthritis.
نویسندگان
چکیده
Regulatory T (Treg) cells have emerged as a distinct subset of lymphocytes that are responsible for limiting immune responses and avoiding pathologic autoimmunity. Evidence is accumulating that defects in Treg function are important in immune-mediated diseases such as rheumatoid arthritis (RA). We discuss herein the biology of Treg cells and emphasize what is known about Treg dysfunction in RA.
منابع مشابه
Regulatory T cells in rheumatoid arthritis
Regulatory T cells have attracted substantial interest in connection with their role in controlling autoimmunity and the possibility that they could be used therapeutically. Here, we summarize the current understanding of the several subsets of regulatory T cells and defects in their function in rheumatoid arthritis. In evaluating the possibility of using regulatory T cells to treat rheumatoid ...
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عنوان ژورنال:
- Arthritis and rheumatism
دوره 56 3 شماره
صفحات -
تاریخ انتشار 2007